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Modified Organism
BCS-GHØØ2-5 - GlyTol™ Cotton GHB614
Record information and status
Record ID
Date of creation
2008-08-13 15:16 UTC (manoela.miranda@cbd.int)
Date of last update
2013-01-28 19:19 UTC (dina.abdelhakim@cbd.int)
Date of publication
2013-01-28 19:19 UTC (dina.abdelhakim@cbd.int)

Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.

LMO name
GlyTol™ Cotton GHB614
Transformation event
Unique identifier
Bayer CropScience
GlyTol cotton event GHB614 contains a stably integrated gene 2mepsps. The 2mepsps gene was generated by introducing mutations into the wild-type epsps (wt epsps) gene from maize, leading to a double mutant EPSPS protein with two amino acid substitutions (2mEPSPS). This modification confers the protein a decreased binding affinity for glyphosate, allowing it to maintain sufficient enzymatic activity in the presence of the herbicide. Therefore, the plants bearing this gene are tolerant to glyphosate herbicides.
Recipient Organism or Parental Organisms
The term Recipient organism refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas Parental organisms refers to those that were involved in cross breeding or cell fusion.
Gossypium hirsutum - Cotton
Point of collection or acquisition of the recipient organism
Variety: Coker 312
Characteristics of the transformation process
Techniques used for the modification
  • Agrobacterium-mediated DNA transfer
Genetic elements construct
Ti plasmid left border repeat
0.02 Kb
Histone H4 gene Promoter
1.01 Kb
Histone H3 Gene II intron 1
0.52 Kb
Optimized Transit Peptide
0.37 Kb
5-enolpyruvylshikimate-3-phosphate synthase
1.34 Kb
Histone H4 gene 3' UTR
0.74 Kb
Ti plasmid right border repeat
0.02 Kb
Further details
Notes regarding the genetic elements introduced or modified in this LMO
Southern blot analysis indicated that a single insertion of the complete T-DNA as constructed occurred in the GHB614 line. There was no indication that any portion of the vector backbone also integrated into the GHB614 line.
LMO characteristics
Modified traits
Common use(s)
  • Food
  • Feed
  • Fiber/textile

Records referencing this document (65)
65record(s) found
Country's Decision or any other Communication21 records
Information Resource1 record
Modified Organism14 records
Organization6 records
Risk Assessment23 records